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Friday, April 25, 2008  

Amperometric glucose biosensor based on boron-doped CNTs modified electrode

Glassy carbon (GC) electrode modified with B-doped carbon nanotubes (BCNTs) shows high electrocatalytic activity for the oxidation of H2O2 due to the large amount of edge sites and oxygen-rich groups located at the defective sites induced by boron doping.
A glucose biosensor based on the GC/BCNTs/Poly(o-aminophenol)-Glucose oxidase electrode exhibits the good characteristics for the glucose determination: such as high sensitivity (171.2 nA mM-1), low detection limit (3.6 microM), wide linear range (up to 8 mM), short response time (within 6 s), satisfactory anti-interference ability and good stability. The apparent Michaelis-Menten constant of the immobilized glucose oxidase is 15.19 mM. These imply that the BCNTs have potential application in constructing enzyme based amperometric biosensors.
Source: Talanta (2008), article in press

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